ATXN7L3 抗体 (Internal Region)
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- 抗原 See all ATXN7L3 抗体
- ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATXN7L3 antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- ATXN7L3 Antibody detects endogenous levels of total ATXN7L3.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ATXN7L3, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ATXN7L3 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
- 别名
- ATXN7L3 (ATXN7L3 产品)
- 别名
- E030022H21Rik antibody, si:busm1-180g5.4 antibody, si:dz180g5.4 antibody, wu:fj12f07 antibody, zgc:136438 antibody, zgc:158566 antibody, ataxin 7 like 3 antibody, ataxin 7-like 3 antibody, ATXN7L3 antibody, Atxn7l3 antibody, atxn7l3 antibody
- 背景
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Description: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B (PubMed:18206972, PubMed:21746879). The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex (PubMed:18206972). Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B (PubMed:27601583).
Gene: ATXN7L3
- 分子量
- 39 kDa
- 基因ID
- 56970
- UniProt
- Q14CW9
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