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ATXN7L3 抗体 (Internal Region)

ATXN7L3 适用: 人, 小鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260152
发货至: 中国
  • 抗原 See all ATXN7L3 抗体
    ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
    抗原表位
    • 5
    • 2
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 17
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 17
    克隆类型
    • 17
    多克隆
    标记
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATXN7L3 antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    ATXN7L3 Antibody detects endogenous levels of total ATXN7L3.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ATXN7L3, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ATXN7L3 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
    别名
    ATXN7L3 (ATXN7L3 产品)
    别名
    E030022H21Rik antibody, si:busm1-180g5.4 antibody, si:dz180g5.4 antibody, wu:fj12f07 antibody, zgc:136438 antibody, zgc:158566 antibody, ataxin 7 like 3 antibody, ataxin 7-like 3 antibody, ATXN7L3 antibody, Atxn7l3 antibody, atxn7l3 antibody
    背景

    Description: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B (PubMed:18206972, PubMed:21746879). The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex (PubMed:18206972). Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B (PubMed:27601583).

    Gene: ATXN7L3

    分子量
    39 kDa
    基因ID
    56970
    UniProt
    Q14CW9
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