ASPM 抗体 (Internal Region)
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- 抗原 See all ASPM 抗体
- ASPM (Asp (Abnormal Spindle) Homolog, Microcephaly Associated (ASPM))
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抗原表位
- Internal Region
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASPM antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blotting (WB)
- 特异性
- ASPM Antibody detects endogenous levels of total ASPM.
- 预测反应
- Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ASPM, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ASPM Primary Antibody
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- 应用备注
- WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ASPM (Asp (Abnormal Spindle) Homolog, Microcephaly Associated (ASPM))
- 别名
- ASPM (ASPM 产品)
- 别名
- Calmbp1 antibody, ASPM antibody, ASP antibody, MCPH5 antibody, D330028K02Rik antibody, Sha1 antibody, abnormal spindle microtubule assembly antibody, asp (abnormal spindle)-like, microcephaly associated (Drosophila) antibody, Aspm antibody, ASPM antibody, aspm antibody
- 背景
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Description: Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex (PubMed:28436967). May have a preferential role in regulating neurogenesis.
Gene: ASPM
- 分子量
- 410 kDa
- 基因ID
- 259266
- UniProt
- Q8IZT6
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