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- 抗原 See all ASIP 抗体
- ASIP (Agouti Signaling Protein (ASIP))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASIP antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 特异性
- ASIP Antibody detects endogenous levels of total ASIP.
- 预测反应
- Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ASIP, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ASIP Primary Antibody
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anti-Agouti Signaling Protein (ASIP) (AA 23-112) antibody
ASIP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Agouti Signaling Protein (ASIP) antibodyASIP 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ASIP (Agouti Signaling Protein (ASIP))
- 别名
- ASIP (ASIP 产品)
- 别名
- AGSW antibody, AGTI antibody, AGTIL antibody, ASP antibody, SHEP9 antibody, ASIP antibody, AA960621 antibody, AI256638 antibody, D8Ertd580e antibody, PAR-3 antibody, Par3 antibody, Pard3a antibody, agouti signaling protein antibody, par-3 family cell polarity regulator antibody, ASIP antibody, Asip antibody, asip antibody, Pard3 antibody
- 背景
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Description: Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.
Gene: ASIP
- 分子量
- 14 kDa
- 基因ID
- 434
- UniProt
- P42127
- 途径
- Cell-Cell Junction Organization, Feeding Behaviour
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