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- 抗原 See all PYDC1 抗体
- PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PYDC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- ASC2 Antibody detects endogenous levels of total ASC2
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ASC2
- 亚型
- IgG
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- 应用备注
- WB 1:1000-3000 IHC 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))
- 别名
- ASC2 (PYDC1 产品)
- 别名
- ASC2 antibody, POP1 antibody, PYC1 antibody, pyrin domain containing 1 antibody, PYDC1 antibody
- 背景
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Description: Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.
Gene: PYDC1
- 分子量
- 10 kDa
- 基因ID
- 260434
- UniProt
- Q8WXC3
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