ARID1A 抗体 (Internal Region)
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- 抗原 See all ARID1A 抗体
- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARID1A antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- ARI1A Antibody detects endogenous levels of total ARI1A.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ARI1A, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ARID1A Primary Antibody
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anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) antibody
ARID1A 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (AA 655-816) antibodyARID1A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (AA 1717-1750) antibodyARID1A 适用: 人 WB 宿主: 兔 Polyclonal RB53540 unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (AA 1930-1964) antibodyARID1A 适用: 人 WB 宿主: 兔 Polyclonal RB53541 unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
- 别名
- ARID1A (ARID1A 产品)
- 别名
- B120 antibody, BAF250 antibody, BAF250a antibody, BM029 antibody, C1orf4 antibody, ELD antibody, MRD14 antibody, OSA1 antibody, P270 antibody, SMARCF1 antibody, hELD antibody, hOSA1 antibody, 1110030E03Rik antibody, Osa1 antibody, Smarcf1 antibody, ARID1A antibody, wu:fb79b07 antibody, wu:fb95g08 antibody, zgc:171438 antibody, AT-rich interaction domain 1A antibody, AT rich interactive domain 1A (SWI-like) antibody, AT rich interactive domain 1Aa (SWI-like) antibody, ARID1A antibody, Arid1a antibody, arid1a antibody, arid1aa antibody
- 背景
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Description: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Gene: ARID1A
- 分子量
- 242kDa
- 基因ID
- 8289
- UniProt
- O14497
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
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