ARID1A 抗体 (Internal Region)
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- 抗原 See all ARID1A 抗体
- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARID1A antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- ARI1A Antibody detects endogenous levels of total ARI1A.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ARI1A, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ARID1A Primary Antibody
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anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) antibody
ARID1A 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (AA 655-816) antibodyARID1A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (AA 1717-1750) antibodyARID1A 适用: 人 WB 宿主: 兔 Polyclonal RB53540 unconjugated
anti-AT Rich Interactive Domain 1A (SWI-Like) (ARID1A) (AA 1930-1964) antibodyARID1A 适用: 人 WB 宿主: 兔 Polyclonal RB53541 unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))
- 别名
- ARID1A (ARID1A 产品)
- 背景
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Description: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Gene: ARID1A
- 分子量
- 242kDa
- 基因ID
- 8289
- UniProt
- O14497
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation
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