APLF 抗体 (Internal Region)
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- 抗原 See all APLF 抗体
- APLF (Aprataxin and PNKP Like Factor (APLF))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APLF antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- APLF Antibody detects endogenous levels of total APLF.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human APLF, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product APLF Primary Antibody
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- 应用备注
- WB: 1:500-1:3000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- APLF (Aprataxin and PNKP Like Factor (APLF))
- 别名
- APLF (APLF 产品)
- 别名
- apfl antibody, palf antibody, xip1 antibody, APLF antibody, C2orf13 antibody, DKFZp459J1223 antibody, APFL antibody, PALF antibody, Xip1 antibody, 2010301N04Rik antibody, AI452191 antibody, RGD1565557 antibody, aprataxin and PNKP like factor antibody, APLF antibody, aplf antibody, Aplf antibody
- 背景
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Description: Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
Gene: APLF
- 分子量
- 57kDa
- 基因ID
- 200558
- UniProt
- Q8IW19
- 途径
- DNA Damage Repair
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