APLF 抗体 (Internal Region)
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- 抗原 See all APLF 抗体
- APLF (Aprataxin and PNKP Like Factor (APLF))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APLF antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- APLF Antibody detects endogenous levels of total APLF.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human APLF, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product APLF Primary Antibody
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- 应用备注
- WB: 1:500-1:3000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- APLF (Aprataxin and PNKP Like Factor (APLF))
- 别名
- APLF (APLF 产品)
- 背景
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Description: Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
Gene: APLF
- 分子量
- 57kDa
- 基因ID
- 200558
- UniProt
- Q8IW19
- 途径
- DNA Damage Repair
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