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- 抗原 See all PRKAG2 抗体
- PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKAG2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- AMPKgamma2 Antibody detects endogenous levels of total AMPKgamma2.
- 预测反应
- Pig,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human AMPKgamma2, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PRKAG2 Primary Antibody
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anti-Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2) (AA 1-328) antibody
PRKAG2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2) (C-Term) antibodyPRKAG2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2) (AA 191-300) antibodyPRKAG2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2) (full length) antibodyPRKAG2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2) (AA 1-328) antibodyPRKAG2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2) (N-Term) antibodyPRKAG2 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2) (AA 290-508) antibodyPRKAG2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2) antibodyPRKAG2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2) (N-Term) antibodyPRKAG2 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2) (AA 1-50) antibodyPRKAG2 适用: 人, 小鼠 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))
- 别名
- PRKAG2 (PRKAG2 产品)
- 别名
- MGC82938 antibody, PRKAG2 antibody, si:ch211-230l11.1 antibody, si:dkey-217f4.2 antibody, AAKG antibody, AAKG2 antibody, CMH6 antibody, H91620p antibody, WPWS antibody, 2410051C13Rik antibody, AI854673 antibody, protein kinase AMP-activated non-catalytic subunit gamma 2 antibody, protein kinase, AMP-activated, gamma 2 non-catalytic subunit L homeolog antibody, 5'-AMP-activated protein kinase subunit gamma-2 antibody, protein kinase, AMP-activated, gamma 2 non-catalytic subunit b antibody, protein kinase, AMP-activated, gamma 2 non-catalytic subunit antibody, Prkag2 antibody, PRKAG2 antibody, prkag2.L antibody, LOC504219 antibody, prkag2b antibody, prkag2 antibody
- 背景
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Description: AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
Gene: PRKAG2
- 分子量
- 65kDa
- 基因ID
- 51422
- UniProt
- Q9UGJ0
- 途径
- AMPK Signaling, Cellular Glucan Metabolic Process, Ribonucleoside Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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