AKR1C4 抗体
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- 抗原 See all AKR1C4 抗体
- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AKR1C4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- AKR1C4 Antibody detects endogenous levels of total AKR1C4
- 交叉反应
- 人, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human AKR1C4
- 亚型
- IgG
- Top Product
- Discover our top product AKR1C4 Primary Antibody
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- 应用备注
- WB 1:1000-3000 IHC 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
- 别名
- AKR1C4 (AKR1C4 产品)
- 别名
- 3-alpha-HSD antibody, C11 antibody, CDR antibody, CHDR antibody, DD-4 antibody, DD4 antibody, HAKRA antibody, aldo-keto reductase family 1 member C4 antibody, AKR1C4 antibody
- 背景
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Description: Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Gene: AKR1C4
- 分子量
- 37 kDa
- 基因ID
- 1109
- UniProt
- P17516
- 途径
- Steroid Hormone Biosynthesis
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