AIMP1 抗体 (Internal Region)
-
- 抗原 See all AIMP1 抗体
- AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This AIMP1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 特异性
- AIMP1 Antibody detects endogenous levels of total AIMP1.
- 预测反应
- Pig,Bovine,Horse,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human AIMP1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product AIMP1 Primary Antibody
-
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
- 别名
- AIMP1 (AIMP1 产品)
- 别名
- EMAP2 antibody, EMAPII antibody, HLD3 antibody, SCYE1 antibody, p43 antibody, wu:fa95a05 antibody, zgc:154081 antibody, AIMP1 antibody, 9830137A06Rik antibody, AIMP1/p43 antibody, Emap2 antibody, Scye1 antibody, scye1 antibody, aminoacyl tRNA synthetase complex interacting multifunctional protein 1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog antibody, AIMP1 antibody, aimp1 antibody, Aimp1 antibody, aimp1.S antibody
- 背景
-
Description: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase (PubMed:10358004). Binds tRNA. Possesses inflammatory cytokine activity (PubMed:11306575). Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation (By similarity). Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels (By similarity). Promotes dermal fibroblast proliferation and wound repair (PubMed:16472771). Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum (By similarity). Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations (PubMed:12237313). Induces maturation of dendritic cells and monocyte cell adhesion (PubMed:11818442). Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (PubMed:19362550).
Gene: AIMP1
- 分子量
- 34kDa
- 基因ID
- 9255
- UniProt
- Q12904
-