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Acylglycerol Kinase 抗体 (C-Term)

AGK 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259823
发货至: 中国
  • 抗原 See all Acylglycerol Kinase (AGK) 抗体
    Acylglycerol Kinase (AGK)
    抗原表位
    • 6
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    C-Term
    适用
    • 27
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    人, 小鼠
    宿主
    • 24
    • 3
    • 1
    克隆类型
    • 27
    • 1
    多克隆
    标记
    • 17
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    This Acylglycerol Kinase antibody is un-conjugated
    应用范围
    • 17
    • 8
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    AGK Antibody detects endogenous levels of total AGK.
    预测反应
    Bovine,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human AGK, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product AGK Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Acylglycerol Kinase (AGK)
    别名
    AGK (AGK 产品)
    别名
    mulk antibody, CATC5 antibody, CTRCT38 antibody, MTDPS10 antibody, MULK antibody, 2610037M15Rik antibody, 6720408I04Rik antibody, AI465370 antibody, Mulk antibody, RGD1562046 antibody, fi38e09 antibody, wu:fi38e09 antibody, zgc:55462 antibody, acylglycerol kinase antibody, acylglycerol kinase S homeolog antibody, AGK antibody, agk antibody, LOC100165096 antibody, Agk antibody, agk.S antibody
    背景

    Description: Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively (PubMed:15939762). Does not phosphorylate sphingosine (PubMed:15939762). Independently of its lipid kinase activity, acts as a component of the TIM22 complex (PubMed:28712724, PubMed:28712726). The TIM22 complex mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane by forming a twin-pore translocase that uses the membrane potential as the external driving force (PubMed:28712724, PubMed:28712726). In the TIM22 complex, required for the import of a subset of metabolite carriers into mitochtondria, such as ANT1/SLC25A4 and SLC25A24, while it is not required for the import of TIMM23 (PubMed:28712724). Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth (PubMed:15939762).

    Gene: AGK

    分子量
    47 kDa
    基因ID
    55750
    UniProt
    Q53H12
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