Acylglycerol Kinase 抗体 (C-Term)
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- 抗原 See all Acylglycerol Kinase (AGK) 抗体
- Acylglycerol Kinase (AGK)
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Acylglycerol Kinase antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- AGK Antibody detects endogenous levels of total AGK.
- 预测反应
- Bovine,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human AGK, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product AGK Primary Antibody
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- 应用备注
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Acylglycerol Kinase (AGK)
- 别名
- AGK (AGK 产品)
- 别名
- mulk antibody, CATC5 antibody, CTRCT38 antibody, MTDPS10 antibody, MULK antibody, 2610037M15Rik antibody, 6720408I04Rik antibody, AI465370 antibody, Mulk antibody, RGD1562046 antibody, fi38e09 antibody, wu:fi38e09 antibody, zgc:55462 antibody, acylglycerol kinase antibody, acylglycerol kinase S homeolog antibody, AGK antibody, agk antibody, LOC100165096 antibody, Agk antibody, agk.S antibody
- 背景
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Description: Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively (PubMed:15939762). Does not phosphorylate sphingosine (PubMed:15939762). Independently of its lipid kinase activity, acts as a component of the TIM22 complex (PubMed:28712724, PubMed:28712726). The TIM22 complex mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane by forming a twin-pore translocase that uses the membrane potential as the external driving force (PubMed:28712724, PubMed:28712726). In the TIM22 complex, required for the import of a subset of metabolite carriers into mitochtondria, such as ANT1/SLC25A4 and SLC25A24, while it is not required for the import of TIMM23 (PubMed:28712724). Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth (PubMed:15939762).
Gene: AGK
- 分子量
- 47 kDa
- 基因ID
- 55750
- UniProt
- Q53H12
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