ADRM1 抗体 (Internal Region)
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- 抗原 See all ADRM1 (Adrm1) 抗体
- ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADRM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- ADRM1 Antibody detects endogenous levels of total ADRM1.
- 预测反应
- Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ADRM1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product Adrm1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))
- 别名
- ADRM1 (Adrm1 产品)
- 别名
- arm-1 antibody, gp110 antibody, rpn13 antibody, xoom antibody, ADRM1 antibody, adrm1 antibody, ARM-1 antibody, ARM1 antibody, GP110 antibody, 1110063P18Rik antibody, 2510006J17Rik antibody, AA408205 antibody, AU043535 antibody, Arm1 antibody, Gp110 antibody, Rpn13 antibody, adrm1a antibody, adrm1b antibody, fa12d09 antibody, wu:fa10g10 antibody, wu:fa12d09 antibody, zgc:56107 antibody, zgc:77256 antibody, adhesion regulating molecule 1 antibody, ADRM1 antibody, 19S proteasome regulatory subunit antibody, ADRM1 protein antibody, adrm1 antibody, ADRM1 antibody, CpipJ_CPIJ002929 antibody, SJAG_04211 antibody, Adrm1 antibody
- 背景
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Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.
Gene: ADRM1
- 分子量
- 46 kDa
- 基因ID
- 11047
- UniProt
- Q16186
- 途径
- Positive Regulation of Endopeptidase Activity
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