Adrenomedullin 抗体 (N-Term)
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- 抗原 See all Adrenomedullin (ADM) 抗体
- Adrenomedullin (ADM)
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Adrenomedullin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- ADM Antibody detects endogenous levels of total ADM.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ADM, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ADM Primary Antibody
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- 应用备注
- WB 1:500-2000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Adrenomedullin (ADM)
- 别名
- ADM (ADM 产品)
- 别名
- ADM antibody, Ap antibody, H39316 antibody, RATAP antibody, AM antibody, adrenomedullin antibody, ADM antibody, adm antibody, Adm antibody
- 物质类
- Hormone
- 背景
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Description: AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Gene: ADM
- 分子量
- 20 kDa
- 基因ID
- 133
- UniProt
- P35318
- 途径
- Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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