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TADA2L 抗体

TADA2A 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259764
发货至: 中国
  • 抗原 See all TADA2L (TADA2A) 抗体
    TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
    适用
    • 45
    • 19
    • 19
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠, 猴
    宿主
    • 42
    • 3
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 28
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TADA2L antibody is un-conjugated
    应用范围
    • 38
    • 22
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    ADA2L antibody detects endogenous levels of total ADA2L
    交叉反应
    人, 猴, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ADA2L
    亚型
    IgG
  • 应用备注
    WB: 1:500~1:3000, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
    别名
    ADA2L (TADA2A 产品)
    别名
    MGC81519 antibody, TADA2A antibody, TADA2L antibody, ADA2 antibody, ADA2A antibody, hADA2 antibody, AV319371 antibody, D030022J10Rik antibody, Tada2l antibody, tada2l antibody, zgc:154057 antibody, transcriptional adaptor 2A L homeolog antibody, transcriptional adaptor 2A antibody, tada2a.L antibody, TADA2A antibody, Tada2a antibody, tada2a antibody
    背景

    Description: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376). May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376).

    Gene: TADA2A

    分子量
    47kDa
    基因ID
    6871
    UniProt
    O75478
    途径
    Chromatin Binding
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