TADA2L 抗体
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- 抗原 See all TADA2L (TADA2A) 抗体
- TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
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适用
- 人, 小鼠, 大鼠, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TADA2L antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- ADA2L antibody detects endogenous levels of total ADA2L
- 交叉反应
- 人, 猴, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ADA2L
- 亚型
- IgG
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- 应用备注
- WB: 1:500~1:3000, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
- 别名
- ADA2L (TADA2A 产品)
- 别名
- MGC81519 antibody, TADA2A antibody, TADA2L antibody, ADA2 antibody, ADA2A antibody, hADA2 antibody, AV319371 antibody, D030022J10Rik antibody, Tada2l antibody, tada2l antibody, zgc:154057 antibody, transcriptional adaptor 2A L homeolog antibody, transcriptional adaptor 2A antibody, tada2a.L antibody, TADA2A antibody, Tada2a antibody, tada2a antibody
- 背景
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Description: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376). May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376).
Gene: TADA2A
- 分子量
- 47kDa
- 基因ID
- 6871
- UniProt
- O75478
- 途径
- Chromatin Binding
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