NEMF 抗体 (C-Term)
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- 抗原 See all NEMF (SDCCAG1) 抗体
- NEMF (SDCCAG1) (serologically Defined Colon Cancer Antigen 1 (SDCCAG1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NEMF antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- SDCG1 Antibody detects endogenous levels of total SDCG1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SDCG1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NEMF (SDCCAG1) (serologically Defined Colon Cancer Antigen 1 (SDCCAG1))
- 别名
- NEMF (SDCCAG1 产品)
- 别名
- NY-CO-1 antibody, SDCCAG1 antibody, 1500011I12Rik antibody, 4933405E14Rik antibody, Sdccag1 antibody, nuclear export mediator factor antibody, NEMF antibody, Nemf antibody
- 背景
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Description: Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex (PubMed:25578875). May indirectly play a role in nuclear export (PubMed:16103875).
Gene: NEMF
- 分子量
- 123 kDa
- 基因ID
- 9147
- UniProt
- O60524
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