Pre-mRNA Branch Site Protein p14 (SF3B14) (C-Term) 抗体
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- 抗原 See all Pre-mRNA Branch Site Protein p14 (SF3B14) 抗体
- Pre-mRNA Branch Site Protein p14 (SF3B14)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- SF3B14 Antibody detects endogenous levels of total SF3B14.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SF3B14, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SF3B14 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Pre-mRNA Branch Site Protein p14 (SF3B14)
- 别名
- SF3B6 (SF3B14 产品)
- 别名
- 6030419K15Rik antibody, AV001342 antibody, Sf3b14 antibody, zgc:86708 antibody, HSPC175 antibody, Ht006 antibody, P14 antibody, SAP14 antibody, SF3B14a antibody, splicing factor 3B, subunit 6 antibody, splicing factor 3b, subunit 6 antibody, splicing factor 3b subunit 6 S homeolog antibody, splicing factor 3b subunit 6 antibody, Sf3b6 antibody, sf3b6 antibody, sf3b6.S antibody, SF3B6 antibody
- 背景
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Description: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (PubMed:12234937). Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively (PubMed:16432215).
Gene: SF3B6
- 分子量
- 20 kDa
- 基因ID
- 51639
- UniProt
- Q9Y3B4
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