NSG1 抗体 (Internal Region)
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- 抗原 See all NSG1 (D4S234E) 抗体
- NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NSG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- NSG1 Antibody detects endogenous levels of total NSG1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NSG1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product D4S234E Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
- 别名
- NSG1 (D4S234E 产品)
- 别名
- D4S234 antibody, D4S234E antibody, NEEP21 antibody, P21 antibody, Neep21 antibody, m234 antibody, p21 antibody, Bsmrb antibody, PEP1 antibody, neuronal vesicle trafficking associated 1 antibody, neuron specific gene family member 1 antibody, NSG1 antibody, Nsg1 antibody
- 背景
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Description: Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity). In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage (PubMed:20599942, PubMed:20878061).
Gene: NSG1
- 分子量
- 26 kDa
- 基因ID
- 27065
- UniProt
- P42857
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