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NSG1 抗体 (Internal Region)

D4S234E 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259604
发货至: 中国
  • 抗原 See all NSG1 (D4S234E) 抗体
    NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
    抗原表位
    • 15
    • 10
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 29
    • 26
    • 16
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 41
    • 3
    • 1
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 19
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NSG1 antibody is un-conjugated
    应用范围
    • 45
    • 28
    • 13
    • 13
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    NSG1 Antibody detects endogenous levels of total NSG1.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human NSG1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product D4S234E Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
    别名
    NSG1 (D4S234E 产品)
    别名
    D4S234 antibody, D4S234E antibody, NEEP21 antibody, P21 antibody, Neep21 antibody, m234 antibody, p21 antibody, Bsmrb antibody, PEP1 antibody, neuronal vesicle trafficking associated 1 antibody, neuron specific gene family member 1 antibody, NSG1 antibody, Nsg1 antibody
    背景

    Description: Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity). In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage (PubMed:20599942, PubMed:20878061).

    Gene: NSG1

    分子量
    26 kDa
    基因ID
    27065
    UniProt
    P42857
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