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YOD1 抗体 (Internal Region)

YOD1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259576
发货至: 中国
  • 抗原 See all YOD1 抗体
    YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))
    抗原表位
    • 9
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 34
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 34
    克隆类型
    • 34
    多克隆
    标记
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This YOD1 antibody is un-conjugated
    应用范围
    • 23
    • 18
    • 14
    • 13
    • 5
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    YOD1 Antibody detects endogenous levels of total YOD1.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human YOD1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product YOD1 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))
    别名
    YOD1 (YOD1 产品)
    别名
    DUBA8 antibody, OTUD2 antibody, PRO0907 antibody, hshin7 antibody, wu:fe01a10 antibody, zgc:112182 antibody, 9930028C20Rik antibody, Hshin7 antibody, YOD1 deubiquitinase antibody, YOD1 deubiquitinase L homeolog antibody, YOD1 antibody, Yod1 antibody, yod1.L antibody, yod1 antibody
    背景

    Description: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. May recruit PLAA, UBXN6 and VCP to damaged lysosome membranes decorated with K48-linked ubiquitin chains and remove these chains allowing autophagosome formation (PubMed:27753622).

    Gene: YOD1

    分子量
    35 kDa
    基因ID
    55432
    UniProt
    Q5VVQ6
    途径
    ER-Nucleus Signaling
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