WEE2 抗体
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- 抗原 See all WEE2 抗体
- WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
- 适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WEE2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- WEE2 Antibody detects endogenous levels of total WEE2
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide
- 亚型
- IgG
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- 应用备注
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
- 别名
- WEE2 (WEE2 产品)
- 别名
- Xe-wee1 antibody, wee1 antibody, wee1-b antibody, wee1a antibody, wee1b antibody, wee2-b antibody, xwee1 antibody, xwee2 antibody, WEE1B antibody, Gm1065 antibody, Wee1B antibody, WEE2 antibody, im:5913035 antibody, si:ch211-238n5.5 antibody, wu:fi13b10 antibody, zgc:123074 antibody, WEE1 homolog 2 antibody, WEE1 homolog 2 (S. pombe) antibody, wee2 antibody, WEE2 antibody, Wee2 antibody
- 背景
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Description: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).
Gene: WEE2
- 分子量
- 60 kDa
- 基因ID
- 494551
- UniProt
- P0C1S8
- 途径
- M Phase
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