RFTN1 抗体 (Internal Region)
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- 抗原 See all RFTN1 抗体
- RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFTN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- RFTN1 Antibody detects endogenous levels of total RFTN1.
- 预测反应
- Horse,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RFTN1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RFTN1 Primary Antibody
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anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 288-520) antibody
RFTN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 207-451) antibodyRFTN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (C-Term) antibodyRFTN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 169-198) antibodyRFTN1 适用: 人 WB 宿主: 兔 Polyclonal RB41751 unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) antibodyRFTN1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
- 别名
- RFTN1 (RFTN1 产品)
- 别名
- RAFTLIN antibody, RGD1310777 antibody, RGD1563347 antibody, 2310015n21rik antibody, mig2 antibody, pig9 antibody, pib10 antibody, raftlin antibody, DKFZp459B0154 antibody, 2310015N21Rik antibody, AI853526 antibody, PIB10 antibody, PIG9 antibody, raftlin, lipid raft linker 1 antibody, raftlin lipid raft linker 1 antibody, RFTN1 antibody, Rftn1 antibody, rftn1 antibody
- 背景
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Description: Involved in protein trafficking via association with clathrin and AP2 complex (PubMed:27022195, PubMed:21266579). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages, and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195, PubMed:21266579). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216). May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed:12805216).
Gene: RFTN1
- 分子量
- 63 kDa
- 基因ID
- 23180
- UniProt
- Q14699
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