ALKBH5 抗体 (Internal Region)
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- 抗原 See all ALKBH5 抗体
- ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ALKBH5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- ALKBH5 Antibody detects endogenous levels of total ALKBH5.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ALKBH5, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ALKBH5 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
- 别名
- ALKBH5 (ALKBH5 产品)
- 别名
- RGD1309496 antibody, ABH5 antibody, OFOXD antibody, OFOXD1 antibody, AW050020 antibody, AW215868 antibody, Abh5 antibody, E130207K11 antibody, Ofoxd antibody, alkB homolog 5, RNA demethylase antibody, alkB homolog 5, RNA demethylase L homeolog antibody, Alkbh5 antibody, alkbh5.L antibody, ALKBH5 antibody
- 背景
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Description: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N6-methyladenosine in single-stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).
Gene: ALKBH5
- 分子量
- ?44 kDa
- 基因ID
- 54890
- UniProt
- Q6P6C2
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