STK36 抗体 (Internal Region)
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- 抗原 See all STK36 抗体
- STK36 (serine/threonine Kinase 36 (STK36))
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抗原表位
- Internal Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STK36 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- STK36 Antibody detects endogenous levels of total STK36.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human STK36, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product STK36 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- STK36 (serine/threonine Kinase 36 (STK36))
- 别名
- STK36 (STK36 产品)
- 别名
- FU antibody, fused-like antibody, 1700112N14Rik antibody, B930045J24 antibody, Fused antibody, mKIAA1278 antibody, fu antibody, si:dkey-180i4.3 antibody, zgc:152944 antibody, serine/threonine kinase 36 antibody, serine/threonine kinase 36 (fused homolog, Drosophila) antibody, STK36 antibody, Stk36 antibody, stk36 antibody
- 背景
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Description: Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function (By similarity). Essential for construction of the central pair apparatus of motile cilia.
Gene: STK36
- 分子量
- 170 kDa
- 基因ID
- 27148
- UniProt
- Q9NRP7
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