SRSF3 抗体 (C-Term)
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- 抗原 See all SRSF3 抗体
- SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SRSF3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- SFRS3 Antibody detects endogenous levels of total SFRS3.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SFRS3, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SRSF3 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))
- 别名
- SRSF3 (SRSF3 产品)
- 别名
- SFRS3 antibody, SRp20 antibody, AL024116 antibody, Sfrs3 antibody, X16 antibody, sfrs3 antibody, srp20 antibody, SRP20 antibody, si:zc263a23.9 antibody, zgc:86626 antibody, serine and arginine rich splicing factor 3 antibody, serine/arginine-rich splicing factor 3 antibody, serine/arginine-rich splicing factor 3 S homeolog antibody, serine/arginine-rich splicing factor 3a antibody, SRSF3 antibody, Srsf3 antibody, srsf3.S antibody, srsf3a antibody
- 背景
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Description: Splicing factor that specifically promotes exon-inclusion during alternative splicing (PubMed:26876937). Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing (PubMed:26876937). Also functions as export adapter involved in mRNA nuclear export such as of histone H2A (PubMed:11336712, PubMed:18364396). Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity (PubMed:11336712, PubMed:18364396). RNA-binding is semi-sequence specific (PubMed:17036044).
Gene: SRSF3
- 分子量
- 25 kDa
- 基因ID
- 6428
- UniProt
- P84103
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