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SF3B4 抗体 (N-Term)

SF3B4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259186
发货至: 中国
  • 抗原 See all SF3B4 抗体
    SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
    抗原表位
    • 9
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 41
    • 20
    • 19
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 36
    • 5
    • 1
    克隆类型
    • 37
    • 5
    多克隆
    标记
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SF3B4 antibody is un-conjugated
    应用范围
    • 35
    • 23
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    SF3B4 Antibody detects endogenous levels of total SF3B4.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human SF3B4, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product SF3B4 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
    别名
    SF3B4 (SF3B4 产品)
    别名
    chunp6902 antibody, fb36a04 antibody, wu:fb36a04 antibody, 49kDa antibody, SF3b49 antibody, SF3b50 antibody, Sap49 antibody, spx antibody, AFD1 antibody, Hsh49 antibody, SAP49 antibody, Splicing factor 3B subunit 4 antibody, splicing factor 3b, subunit 4 antibody, splicing factor 3b subunit 4 S homeolog antibody, splicing factor 3b subunit 4 antibody, sap-49 antibody, sf3b4 antibody, Sf3b4 antibody, sf3b4.S antibody, SF3B4 antibody
    背景

    Description: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077).

    Gene: SF3B4

    分子量
    55 kDa
    基因ID
    10262
    UniProt
    Q15427
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