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RAD51 Homolog B 抗体

Rad51B 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259179
发货至: 中国
  • 抗原 See all RAD51 Homolog B (Rad51B) 抗体
    RAD51 Homolog B (Rad51B)
    适用
    • 14
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 猴
    宿主
    • 11
    • 2
    • 1
    克隆类型
    • 13
    • 1
    多克隆
    标记
    • 14
    This RAD51 Homolog B antibody is un-conjugated
    应用范围
    • 13
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    RAD51L1 Antibody detects endogenous levels of total RAD51L1
    交叉反应
    人, 猴, 小鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide
    亚型
    IgG
  • 应用备注
    WB 1:500~1:1000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    RAD51 Homolog B (Rad51B)
    别名
    RAD51L1 (Rad51B 产品)
    别名
    R51H2 antibody, RAD51L1 antibody, REC2 antibody, AI553500 antibody, Rad51l1 antibody, mREC2 antibody, ATRAD51B antibody, T17D12.12 antibody, T17D12_12 antibody, RGD1560681 antibody, rad51l1 antibody, wu:fd07f04 antibody, zgc:56581 antibody, RAD51 paralog B antibody, DNA repair (Rad51) family protein antibody, Rad51 DNA recombinase 2 antibody, RAD51B antibody, Rad51b antibody, rad51b antibody
    背景

    Description: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway.

    Gene: RAD51B

    分子量
    45 kDa
    基因ID
    5890
    UniProt
    O15315
    途径
    DNA Damage Repair
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