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nectin-3 抗体 (Internal Region)

NECTIN3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259135
发货至: 中国
  • 抗原 See all nectin-3 (NECTIN3) 抗体
    nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
    抗原表位
    • 15
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    Internal Region
    适用
    • 58
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    人, 小鼠, 大鼠
    宿主
    • 52
    • 8
    • 5
    • 1
    克隆类型
    • 55
    • 11
    多克隆
    标记
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    This nectin-3 antibody is un-conjugated
    应用范围
    • 53
    • 29
    • 13
    • 13
    • 11
    • 8
    • 8
    • 8
    • 5
    • 4
    • 4
    • 3
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    PVRL3 Antibody detects endogenous levels of total PVRL3.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PVRL3, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product NECTIN3 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
    别名
    NECTIN3 (NECTIN3 产品)
    别名
    PVRL3 antibody, CD113 antibody, CDW113 antibody, NECTIN-3 antibody, PPR3 antibody, PRR3 antibody, PVRR3 antibody, 2610301B19Rik antibody, 3000002N23Rik antibody, 4921513D19Rik antibody, AA407785 antibody, AU016832 antibody, AW538082 antibody, nectin cell adhesion molecule 3 antibody, poliovirus receptor-related 3 antibody, Nectin3 antibody, NECTIN3 antibody, PVRL3 antibody, nectin3 antibody
    背景

    Description: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.

    Gene: NECTIN3

    分子量
    61 kDa
    基因ID
    25945
    UniProt
    Q9NQS3
    途径
    Cell-Cell Junction Organization
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