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- 抗原 See all NR5A1 抗体
- NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR5A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Steroidogenic Factor 1 Antibody detects endogenous levels of total Steroidogenic Factor 1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Steroidogenic Factor 1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NR5A1 Primary Antibody
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anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (Middle Region) antibody
NR5A1 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, 兔, Cow, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 172-221) antibodyNR5A1 适用: 人, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (Internal Region) antibodyNR5A1 适用: 人, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 1-120) antibodyNR5A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 64-93), (N-Term) antibodyNR5A1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB26159 unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (Middle Region) antibodyNR5A1 适用: 人, 大鼠, 豚鼠, 犬, 马, 兔, Cow, 绵羊, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) antibodyNR5A1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 174-223) antibodyNR5A1 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 358-407) antibodyNR5A1 适用: 小鼠, 大鼠, 豚鼠, 犬, 马, 兔, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (AA 169-218) antibodyNR5A1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
- 别名
- NR5A1 (NR5A1 产品)
- 别名
- AD4BP antibody, ELP antibody, FTZ1 antibody, FTZF1 antibody, POF7 antibody, SF-1 antibody, SF1 antibody, SPGF8 antibody, SRXY3 antibody, Ad4BP antibody, ELP-3 antibody, Ftz-F1 antibody, Ftzf1 antibody, Ad4BP/SF-1 antibody, Ad4bp antibody, Sf-1 antibody, NR5A1 antibody, sf-1 antibody, elp antibody, sf1 antibody, ftz1 antibody, ad4bp antibody, ftzf1 antibody, SF-1/Ad4BP antibody, SI:zC167P9.2 antibody, ff1d antibody, nr5a2l antibody, nuclear receptor subfamily 5 group A member 1 antibody, nuclear receptor subfamily 5, group A, member 1 antibody, nuclear receptor subfamily 5 group A member 1 L homeolog antibody, nuclear receptor subfamily 6 group A member 1 antibody, nuclear receptor subfamily 5, group A, member 1b antibody, NR5A1 antibody, Nr5a1 antibody, nr5a1.L antibody, nr5a1 antibody, NR6A1 antibody, nr5a1b antibody
- 背景
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Description: Transcriptional activator. Essential for sexual differentiation and formation of the primary steroidogenic tissues (PubMed:27378692). Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1 (PubMed:27378692). The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. Binds phosphatidylcholine (By similarity). Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3. Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Gene: NR5A1
- 分子量
- ?55 kDa
- 基因ID
- 2516
- UniProt
- Q13285
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Maintenance of Protein Location
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