NOC2L 抗体 (C-Term)
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- 抗原 See all NOC2L 抗体
- NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NOC2L antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- NOC2L Antibody detects endogenous levels of total NOC2L.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NOC2L, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NOC2L Primary Antibody
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anti-Nucleolar Complex Associated 2 Homolog (NOC2L) antibody
NOC2L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))
- 别名
- NOC2L (NOC2L 产品)
- 别名
- NET15 antibody, NET7 antibody, NIR antibody, AA410003 antibody, AF155546 antibody, RGD1309387 antibody, NOC2 like nucleolar associated transcriptional repressor antibody, NOC2-like nucleolar associated transcriptional repressor antibody, NOC2L antibody, Noc2l antibody
- 背景
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Description: Acts as an inhibitor of histone acetyltransferase activity, prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter.
Gene: NOC2L
- 分子量
- 85 kDa
- 基因ID
- 26155
- UniProt
- Q9Y3T9
- 途径
- Negative Regulation of intrinsic apoptotic Signaling
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