STK24 抗体 (N-Term)
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- 抗原 See all STK24 抗体
- STK24 (serine/threonine Kinase 24 (STK24))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STK24 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- MST3 Antibody detects endogenous levels of total MST3.
- 预测反应
- Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human MST3, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product STK24 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- STK24 (serine/threonine Kinase 24 (STK24))
- 别名
- STK24 (STK24 产品)
- 别名
- MST3 antibody, MST3B antibody, STE20 antibody, STK3 antibody, 1810013H02Rik antibody, C76483 antibody, MST-3 antibody, Mst3 antibody, Mst3b antibody, RGD1561742 antibody, stk24 antibody, wu:fi29b08 antibody, zgc:66137 antibody, 0610042I06Rik antibody, MST antibody, Mst2 antibody, Ste20 antibody, mess1 antibody, zgc:163071 antibody, mst3 antibody, mst3b antibody, ste20 antibody, stk3 antibody, serine/threonine kinase 24 antibody, serine/threonine kinase 24b (STE20 homolog, yeast) antibody, serine/threonine-protein kinase 24 antibody, serine/threonine kinase 3 antibody, serine/threonine kinase 24a (STE20 homolog, yeast) antibody, serine/threonine kinase 24 L homeolog antibody, STK24 antibody, Stk24 antibody, stk24b antibody, ATEG_04314 antibody, ATEG_09179 antibody, UREG_03984 antibody, BDBG_07988 antibody, MCYG_07323 antibody, Stk3 antibody, stk24a antibody, stk24.L antibody
- 背景
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Description: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006). Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
Gene: STK24
- 分子量
- 50 kDa
- 基因ID
- 8428
- UniProt
- Q9Y6E0
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