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MASTL 抗体 (C-Term)

MASTL 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259099
发货至: 中国
  • 抗原 See all MASTL 抗体
    MASTL (Microtubule Associated serine/threonine Kinase-Like (MASTL))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 45
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 45
    • 14
    克隆类型
    • 44
    • 15
    多克隆
    标记
    • 25
    • 7
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MASTL antibody is un-conjugated
    应用范围
    • 45
    • 37
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    MASTL Antibody detects endogenous levels of total MASTL.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MASTL, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MASTL Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MASTL (Microtubule Associated serine/threonine Kinase-Like (MASTL))
    别名
    MASTL (MASTL 产品)
    别名
    GW antibody, GWL antibody, MAST-L antibody, im:7149025 antibody, wu:fa02a12 antibody, zgc:100990 antibody, MASTL antibody, GREATWALL antibody, RP11-85G18.2 antibody, THC2 antibody, hGWL antibody, 2700091H24Rik antibody, C88295 antibody, greatwall antibody, thc2 antibody, microtubule associated serine/threonine kinase-like antibody, microtubule associated serine/threonine kinase like antibody, serine/threonine-protein kinase greatwall antibody, microtubule associated serine/threonine kinase like L homeolog antibody, mastl antibody, MASTL antibody, LOC100541707 antibody, Mastl antibody, mastl.L antibody
    背景

    Description: Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro, however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.

    Gene: MASTL

    分子量
    97 kDa
    基因ID
    84930
    UniProt
    Q96GX5
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