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MSH3 抗体 (N-Term)

MSH3 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259074
发货至: 中国
  • 抗原 See all MSH3 抗体
    MSH3 (MutS Homolog 3 (MSH3))
    抗原表位
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 33
    • 3
    • 2
    宿主
    • 33
    克隆类型
    • 33
    多克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MSH3 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 11
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    MSH3 Antibody detects endogenous levels of total MSH3.
    预测反应
    Pig,Horse,Sheep,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MSH3, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MSH3 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MSH3 (MutS Homolog 3 (MSH3))
    别名
    MSH3 (MSH3 产品)
    别名
    ATMSH3 antibody, M7J2.90 antibody, M7J2_90 antibody, homolog of DNA mismatch repair protein MSH3 antibody, DUP antibody, MRP1 antibody, D13Em1 antibody, Rep-3 antibody, Rep3 antibody, mutS homolog 3 antibody, DNA mismatch repair protein MSH3 antibody, homolog of DNA mismatch repair protein MSH3 antibody, mismatch repair protein antibody, MSH3 antibody, Msh3 antibody
    背景

    Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

    Gene: MSH3

    分子量
    127 kDa
    基因ID
    4437
    UniProt
    P20585
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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