IKZF4 抗体 (C-Term)
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- 抗原 See all IKZF4 抗体
- IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IKZF4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- IKZF4 Antibody detects endogenous levels of total IKZF4.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human IKZF4, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product IKZF4 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
- 别名
- IKZF4 (IKZF4 产品)
- 别名
- A630026H08Rik antibody, Eos antibody, Zfpn1a4 antibody, Znfn1a4 antibody, EOS antibody, ZNFN1A4 antibody, IKAROS family zinc finger 4 antibody, Ikzf4 antibody, IKZF4 antibody
- 背景
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Description: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 (By similarity).
Gene: IKZF4
- 分子量
- 64 kDa
- 基因ID
- 64375
- UniProt
- Q9H2S9
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