GNL3L 抗体
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- 抗原 See all GNL3L 抗体
- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GNL3L antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- GNL3L Antibody detects endogenous levels of total GNL3L
- 交叉反应
- 人
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide
- 亚型
- IgG
- Top Product
- Discover our top product GNL3L Primary Antibody
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- 应用备注
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
- 别名
- GNL3L (GNL3L 产品)
- 别名
- SI:zK13A21.8 antibody, flj10613 antibody, flj10613l antibody, si:dkey-13a21.8 antibody, zgc:110536 antibody, BC020354 antibody, guanine nucleotide binding protein-like 3 (nucleolar)-like antibody, guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog antibody, G protein nucleolar 3 like antibody, gnl3l antibody, gnl3l.S antibody, GNL3L antibody, Gnl3l antibody
- 背景
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Description: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Gene: GNL3L
- 分子量
- 66 kDa
- 基因ID
- 54552
- UniProt
- Q9NVN8
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