RGS7 抗体 (Internal Region)
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- 抗原 See all RGS7 抗体
- RGS7 (Regulator of G-Protein Signaling 7 (RGS7))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RGS7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- RGS7 Antibody detects endogenous levels of total RGS7.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RGS7, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RGS7 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RGS7 (Regulator of G-Protein Signaling 7 (RGS7))
- 别名
- RGS7 (RGS7 产品)
- 别名
- zgc:92793 antibody, RGS7 antibody, regulator of G-protein signaling 7 antibody, regulator of G protein signaling 7a antibody, regulator of G protein signaling 7 antibody, Regulator of G protein Signaling antibody, RGS7 antibody, rgs7a antibody, CpipJ_CPIJ014798 antibody, Tsp_03415 antibody, rgs-7 antibody, Rgs7 antibody
- 背景
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Description: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). May play a role in synaptic vesicle exocytosis (PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264).
Gene: RGS7
- 分子量
- 65 kDa
- 基因ID
- 6000
- UniProt
- P49802
- 途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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