FZD8 抗体 (N-Term)
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- 抗原 See all FZD8 抗体
- FZD8 (Frizzled Family Receptor 8 (FZD8))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FZD8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- FZD8 Antibody detects endogenous levels of total FZD8.
- 预测反应
- Pig,Bovine,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human FZD8, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product FZD8 Primary Antibody
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anti-Frizzled Family Receptor 8 (FZD8) (AA 55-233) antibody
FZD8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) antibodyFZD8 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (AA 72-161) antibodyFZD8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (Extracellular Domain) antibodyFZD8 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠, Cow, 猴, 非洲爪蟾, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyVerified FZD8 适用: 人 WB, ELISA, IHC, IF, IEM 宿主: 山羊 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyFZD8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyFZD8 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- FZD8 (Frizzled Family Receptor 8 (FZD8))
- 别名
- FZD8 (FZD8 产品)
- 别名
- FZ-8 antibody, hFZ8 antibody, FZD8 antibody, Fz-8 antibody, frizzled8 antibody, xfz8 antibody, Xfz8 antibody, frizzled-8 antibody, hfz8 antibody, Fz8 antibody, fzd8 antibody, fz5 antibody, fz8a antibody, fzc antibody, wu:fd02c05 antibody, zg05 antibody, ZG06 antibody, Zfz8b antibody, fz6 antibody, fz8b antibody, fzA antibody, ik:tdsubc_1e1 antibody, xx:tdsubc_1e1 antibody, zfzA antibody, frizzled class receptor 8 antibody, frizzled class receptor 8 S homeolog antibody, frizzled class receptor 8 L homeolog antibody, frizzled class receptor 8a antibody, frizzled class receptor 8b antibody, FZD8 antibody, fzd8.S antibody, fzd8 antibody, Fzd8 antibody, fzd8.L antibody, fzd8a antibody, fzd8b antibody
- 背景
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Description: Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Coreceptor along with RYK of Wnt proteins, such as WNT1.
Gene: FZD8
- 分子量
- 70 kDa
- 基因ID
- 8325
- UniProt
- Q9H461
- 途径
- WNT signaling
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