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- 抗原 See all BAZ2A 抗体
- BAZ2A (Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A))
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抗原表位
- N-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAZ2A antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- BAZ2A Antibody detects endogenous levels of total BAZ2A.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human BAZ2A, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product BAZ2A Primary Antibody
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anti-Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A) antibody
BAZ2A 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A) (AA 97-266) antibodyBAZ2A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A) (N-Term) antibodyBAZ2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A) (AA 1-1905) antibodyBAZ2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A) antibodyBAZ2A 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- BAZ2A (Bromodomain Adjacent To Zinc Finger Domain, 2A (BAZ2A))
- 别名
- BAZ2A (BAZ2A 产品)
- 别名
- zgc:101601 antibody, tip5 antibody, bax2a antibody, walp3 antibody, TIP5 antibody, WALp3 antibody, AA415431 antibody, C030005G16Rik antibody, C78388 antibody, Tip5 antibody, Walp3 antibody, mKIAA0314 antibody, bromodomain adjacent to zinc finger domain, 2A antibody, bromodomain adjacent to zinc finger domain 2A antibody, bromodomain adjacent to zinc finger domain 2A L homeolog antibody, Baz2a antibody, baz2a antibody, BAZ2A antibody, baz2a.L antibody
- 背景
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Description: Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter, pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity).
Gene: BAZ2A
- 分子量
- 210 kDa
- 基因ID
- 11176
- UniProt
- Q9UIF9
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