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BCL11B 抗体 (Internal Region)

BCL11B 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258605
发货至: 中国
  • 抗原 See all BCL11B 抗体
    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
    抗原表位
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 46
    • 8
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    • 5
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    • 3
    • 2
    • 1
    人, 大鼠
    宿主
    • 45
    • 1
    • 1
    克隆类型
    • 38
    • 9
    多克隆
    标记
    • 25
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
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    This BCL11B antibody is un-conjugated
    应用范围
    • 27
    • 14
    • 10
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    BCL11B Antibody detects endogenous levels of total BCL11B.
    预测反应
    Pig,Bovine,Sheep,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human BCL11B, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product BCL11B Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    有效期
    12 months
  • 抗原
    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
    别名
    BCL11B (BCL11B 产品)
    别名
    BCL11B antibody, 9130430L19Rik antibody, AI604821 antibody, B630002E05Rik antibody, BCL-11B antibody, Ctip2 antibody, Rit1 antibody, ATL1 antibody, ATL1-alpha antibody, ATL1-beta antibody, ATL1-delta antibody, ATL1-gamma antibody, CTIP-2 antibody, CTIP2 antibody, RIT1 antibody, ZNF856B antibody, hRIT1-alpha antibody, B-cell CLL/lymphoma 11B antibody, B cell leukemia/lymphoma 11B antibody, B-cell CLL/lymphoma 11B (zinc finger protein) antibody, BCL11B antibody, Bcl11b antibody
    背景

    Description: Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus (PubMed:27959755). Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4+ T-lymphocytes (PubMed:16809611). Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity). May also function in the P53-signaling pathway (By similarity).

    Gene: BCL11B

    分子量
    ?95 kDa
    基因ID
    64919
    UniProt
    Q9C0K0
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