BCL11B 抗体 (Internal Region)
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- 抗原 See all BCL11B 抗体
- BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
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抗原表位
- Internal Region
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCL11B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- BCL11B Antibody detects endogenous levels of total BCL11B.
- 预测反应
- Pig,Bovine,Sheep,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human BCL11B, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product BCL11B Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
- 别名
- BCL11B (BCL11B 产品)
- 别名
- BCL11B antibody, 9130430L19Rik antibody, AI604821 antibody, B630002E05Rik antibody, BCL-11B antibody, Ctip2 antibody, Rit1 antibody, ATL1 antibody, ATL1-alpha antibody, ATL1-beta antibody, ATL1-delta antibody, ATL1-gamma antibody, CTIP-2 antibody, CTIP2 antibody, RIT1 antibody, ZNF856B antibody, hRIT1-alpha antibody, B-cell CLL/lymphoma 11B antibody, B cell leukemia/lymphoma 11B antibody, B-cell CLL/lymphoma 11B (zinc finger protein) antibody, BCL11B antibody, Bcl11b antibody
- 背景
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Description: Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus (PubMed:27959755). Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4+ T-lymphocytes (PubMed:16809611). Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity). May also function in the P53-signaling pathway (By similarity).
Gene: BCL11B
- 分子量
- ?95 kDa
- 基因ID
- 64919
- UniProt
- Q9C0K0
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