USP44 抗体 (Internal Region)
-
- 抗原 See all USP44 抗体
- USP44 (Ubiquitin Specific Peptidase 44 (USP44))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This USP44 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- USP44 Antibody detects endogenous levels of total USP44.
- 预测反应
- Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human USP44, corresponding to a region within the internal amino acids.
- 亚型
- IgG
-
anti-Ubiquitin Specific Peptidase 44 (USP44) (Internal Region) antibody
USP44 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 44 (USP44) (AA 100-270) antibodyUSP44 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 44 (USP44) (Internal Region) antibodyUSP44 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 44 (USP44) antibodyUSP44 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 44 (USP44) (N-Term) antibodyUSP44 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 44 (USP44) (AA 211-260) antibodyUSP44 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- USP44 (Ubiquitin Specific Peptidase 44 (USP44))
- 别名
- USP44 (USP44 产品)
- 别名
- usp44 antibody, USP49 antibody, E430004F17Rik antibody, zgc:55661 antibody, ubiquitin specific peptidase 44 antibody, ubiquitin specific peptidase 44 L homeolog antibody, ubiquitin specific peptidase 44 S homeolog antibody, USP44 antibody, usp44.L antibody, usp44.S antibody, usp44 antibody, Usp44 antibody
- 背景
-
Description: Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B (H2BK120ub1) ubiquitination.
Gene: USP44
- 分子量
- 81 kDa
- 基因ID
- 84101
- UniProt
- Q9H0E7
- 途径
- M Phase
-
