Usp30 抗体 (N-Term)
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- 抗原 See all Usp30 抗体
- Usp30 (Ubiquitin Specific Peptidase 30 (Usp30))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Usp30 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 特异性
- USP30 Antibody detects endogenous levels of total USP30.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human USP30, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
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anti-Ubiquitin Specific Peptidase 30 (Usp30) (Middle Region) antibody
Usp30 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 30 (Usp30) (AA 57-390) antibodyUsp30 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 30 (Usp30) antibodyUsp30 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 30 (Usp30) (N-Term) antibodyUsp30 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 30 (Usp30) (AA 141-190) antibodyUsp30 适用: 人, 小鼠, 大鼠, 犬, 猴, 豚鼠, 马, 兔, Cow, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 30 (Usp30) (N-Term) antibodyUsp30 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Usp30 (Ubiquitin Specific Peptidase 30 (Usp30))
- 别名
- USP30 (Usp30 产品)
- 别名
- 6330590F17Rik antibody, AI851327 antibody, D5Ertd483e antibody, si:dkey-72n1.2 antibody, ubiquitin specific peptidase 30 antibody, ubiquitin specific peptidase 30 L homeolog antibody, USP30 antibody, usp30 antibody, usp30.L antibody, Usp30 antibody
- 背景
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Description: Deubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy (PubMed:18287522, PubMed:24896179, PubMed:25527291, PubMed:25621951). Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate to mitophagic signaling (PubMed:25621951). Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65' (PubMed:25527291). Acts as negative regulator of mitochondrial fusion by mediating deubiquitination of MFN1 and MFN2 (By similarity).
Gene: USP30
- 分子量
- 60 kDa
- 基因ID
- 84749
- UniProt
- Q70CQ3
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