Nesprin3 抗体 (N-Term)
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- 抗原 See all Nesprin3 (C14orf49) 抗体
- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nesprin3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- C14orf49 Antibody detects endogenous levels of total C14orf49.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human C14orf49, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product C14orf49 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
- 别名
- SYNE3 (C14orf49 产品)
- 别名
- C14orf49 antibody, NET53 antibody, Nesp3 antibody, 4831426I19Rik antibody, nesprin-3 antibody, spectrin repeat containing nuclear envelope family member 3 antibody, spectrin repeat containing, nuclear envelope family member 3 antibody, SYNE3 antibody, Syne3 antibody
- 背景
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Description: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
Gene: SYNE3
- 分子量
- 130 kDa
- 基因ID
- 161176
- UniProt
- Q6ZMZ3
- 途径
- Maintenance of Protein Location
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