TCF7 抗体
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- 抗原 See all TCF7 抗体
- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TCF7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- TCF7 Antibody detects endogenous levels of total TCF7
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide
- 亚型
- IgG
- Top Product
- Discover our top product TCF7 Primary Antibody
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- 应用备注
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
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- 抗原
- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
- 别名
- TCF7 (TCF7 产品)
- 别名
- TCF-1 antibody, AI465550 antibody, Tcf1 antibody, Xtcf-1 antibody, Xtcf1 antibody, tcf-1 antibody, tcf1 antibody, tcf7 antibody, transcription factor 7 antibody, transcription factor 7, T cell specific antibody, transcription factor 7 S homeolog antibody, TCF7 antibody, Tcf7 antibody, tcf7 antibody, tcf7.S antibody
- 背景
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Description: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
Gene: TCF7
- 分子量
- 42 kDa
- 基因ID
- 6932
- UniProt
- P36402
- 途径
- WNT signaling
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