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DDR1 抗体 (Internal Region)

Name: DDR1 抗体 (Internal Region)
SKU: ABIN6258450
Availability: OutOfStock

DDR1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts from rat muscle, using DDR1 Antibody. (DDR1 抗体 (Internal Region))

IF/ICC

2 images

产品编号 ABIN6258450

发货至: 中国

Datasheet as PDF

抗原 See all DDR1 抗体

DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
抗原表位
25

15

10

7

7

7

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
适用
86

41

40

4

2

2

2

2

2

1

1

1
人, 大鼠
宿主
94

7
兔
Compatible Secondaries
克隆类型
94

6

1
多克隆
标记
42

6

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2
This DDR1 antibody is un-conjugated
应用范围
73

36

26

26

21

12

10

6

4

4

3

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

DDR1 Antibody detects endogenous levels of total DDR1.

预测反应

Zebrafish,Horse,Sheep,Rabbit,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human DDR1, corresponding to a region within the internal amino acids.

亚型

IgG

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anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibody
DDR1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 568-829) antibody
DDR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-176) antibody
DDR1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F2C12 unconjugated

anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibody
DDR1 适用: 人 WB, IHC (p), FACS, IF 宿主: 兔 Polyclonal RB14442 unconjugated

anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47), (N-Term) antibody
DDR1 适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01477 unconjugated

anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47) antibody
DDR1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-120) antibody
DDR1 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 396-430) antibody
DDR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50593 unconjugated

anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 22-876) antibody
DDR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (C-Term) antibody
DDR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

别名

DDR1 (DDR1 产品)

别名

CG11573 antibody, CG13984 antibody, CG13985 antibody, CG33531 antibody, CG9488 antibody, CG9490 antibody, CT33540 antibody, DDR antibody, Dmel\\CG33531 antibody, Dmel_CG13984 antibody, 6030432F18 antibody, AI323681 antibody, CD167a antibody, Cak antibody, Nep antibody, PTK3A antibody, CAK antibody, CD167 antibody, EDDR1 antibody, HGK2 antibody, MCK10 antibody, NEP antibody, NTRK4 antibody, PTK3 antibody, RTK6 antibody, TRKE antibody, Drd1 antibody, PTK3D antibody, Discoidin domain receptor antibody, discoidin domain receptor family, member 1 antibody, discoidin domain receptor tyrosine kinase 1 antibody, Ddr antibody, Ddr1 antibody, DDR1 antibody

背景

Description: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
Gene: DDR1

分子量

100 kDa

基因ID

780

UniProt

Q08345

途径

RTK signaling, Smooth Muscle Cell Migration