Chp2 抗体 (Internal Region)
-
- 抗原 See all Chp2 products
- Chp2
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Chp2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC)
- 特异性
- CHP2 Antibody detects endogenous levels of total CHP2.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CHP2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
-
-
- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- Chp2
- Abstract
- Chp2 产品
- 别名
- 2010110P09Rik antibody, Cbhp2 antibody, chp-2 antibody, calcineurin-like EF hand protein 2 antibody, calcineurin like EF-hand protein 2 antibody, Chp2 antibody, CHP2 antibody
- 背景
-
Description: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.
Gene: CHP2
- 分子量
- 22 kDa
- 基因ID
- 63928
- UniProt
- O43745
-