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UBE2D2 抗体 (C-Term)

UBE2D2 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258351
发货至: 中国
  • 抗原 See all UBE2D2 抗体
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    抗原表位
    • 15
    • 12
    • 9
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    • 3
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    • 2
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    • 1
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    C-Term
    适用
    • 67
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    人, 小鼠, 大鼠
    宿主
    • 60
    • 7
    克隆类型
    • 61
    • 6
    多克隆
    标记
    • 33
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    This UBE2D2 antibody is un-conjugated
    应用范围
    • 55
    • 26
    • 13
    • 13
    • 9
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    UBE2D2 Antibody detects endogenous levels of total UBE2D2.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human UBE2D2, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product UBE2D2 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    别名
    UBE2D2 (UBE2D2 产品)
    别名
    E2(17)KB2 antibody, PUBC1 antibody, UBC4 antibody, UBC4/5 antibody, UBCH5B antibody, 1500034D03Rik antibody, Ubc2e antibody, Ube2d2 antibody, ubc4 antibody, ube2d2 antibody, zgc:55886 antibody, E217kB antibody, ubiquitin conjugating enzyme E2 D2 antibody, ubiquitin-conjugating enzyme E2D 2A antibody, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) antibody, ubiquitin-conjugating enzyme E2D 2 antibody, ubiquitin conjugating enzyme E2 D3 antibody, UBE2D2 antibody, Ube2d2a antibody, ube2d2 antibody, Ube2d2 antibody, UBE2D3 antibody
    背景

    Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.

    Gene: UBE2D2

    分子量
    17 kDa
    基因ID
    7322
    UniProt
    P62837
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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