USP19 抗体 (Internal Region)
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- 抗原 See all USP19 抗体
- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP19 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- USP19 Antibody detects endogenous levels of total USP19.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human USP19, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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anti-Ubiquitin Specific Peptidase 19 (USP19) (AA 1-200) antibody
USP19 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 19 (USP19) (Internal Region) antibodyUSP19 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 19 (USP19) antibodyUSP19 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 19 (USP19) (Internal Region) antibodyUSP19 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 19 (USP19) (AA 1-1318) antibodyUSP19 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 19 (USP19) (AA 391-440) antibodyUSP19 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 19 (USP19) (Internal Region) antibodyUSP19 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 19 (USP19) (Internal Region) antibodyUSP19 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
- 别名
- USP19 (USP19 产品)
- 别名
- wu:fc26a05 antibody, si:dkey-32e6.9 antibody, USP19 antibody, MGC145127 antibody, ZMYND9 antibody, 8430421I07Rik antibody, AI047774 antibody, Zmynd9 antibody, ubiquitin specific peptidase 19 antibody, universal stress protein antibody, ubiquitin carboxyl-terminal hydrolase 19 antibody, usp19 antibody, USP19 antibody, RR_RS18085 antibody, PTRG_09611 antibody, Usp19 antibody
- 背景
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Description: Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked ubiquitin chains.
Gene: USP19
- 分子量
- 130 kDa
- 基因ID
- 10869
- UniProt
- O94966
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