IFIT5 抗体 (Internal Region)
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- 抗原 See all IFIT5 products
- IFIT5 (Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IFIT5 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- IFIT5 Antibody detects endogenous levels of total IFIT5.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human IFIT5, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) (AA 107-320) antibody
IFIT5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) antibodyIFIT5 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) (AA 1-482) antibodyIFIT5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) (AA 182-231) antibodyIFIT5 适用: 人, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) (AA 110-159) antibodyIFIT5 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5) (N-Term) antibodyIFIT5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- IFIT5 (Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5))
- 别名
- IFIT5 (IFIT5 产品)
- 别名
- ri58 antibody, DKFZp469M2320 antibody, P58 antibody, RI58 antibody, interferon induced protein with tetratricopeptide repeats 5 antibody, interferon induced protein with tetratricopeptide repeats 5 L homeolog antibody, interferon-induced protein with tetratricopeptide repeats 5 antibody, IFIT5 antibody, ifit5.L antibody, LOC100024963 antibody, LOC100151816 antibody, ifit5 antibody
- 背景
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Description: Interferon-induced RNA-binding protein involved in the human innate immune response. Has a broad and adaptable RNA structure recognition important for RNA recognition specificity in antiviral defense. Binds precursor and processed tRNAs as well as poly-U-tailed tRNA fragments (PubMed:25092312, PubMed:23317505, PubMed:23774268). Specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner (PubMed:23334420). Also recognizes and selectively binds AT-rich dsDNA (PubMed:23774268). Additionally, as a mediator in innate immunity, regulates positively IKK-NFKB signaling by sinergizing the recruitment of IKK to MAP3K7 (PubMed:26334375).
Gene: IFIT5
- 分子量
- 50 kDa
- 基因ID
- 24138
- UniProt
- Q13325
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