Ube2t 抗体 (Internal Region)
-
- 抗原 See all Ube2t 抗体
- Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Ube2t antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- UBE2T Antibody detects endogenous levels of total UBE2T.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human UBE2T, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product Ube2t Primary Antibody
-
-
- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
- 别名
- UBE2T (Ube2t 产品)
- 别名
- PIG50 antibody, UBE2T antibody, 2700084L22Rik antibody, C80607 antibody, RGD1310816 antibody, hspc150 antibody, wu:fj86h11 antibody, zgc:153687 antibody, ubiquitin conjugating enzyme E2 T antibody, ubiquitin-conjugating enzyme E2T antibody, ubiquitin conjugating enzyme E2T S homeolog antibody, ubiquitin-conjugating enzyme E2T (putative) antibody, UBE2T antibody, Ube2t antibody, ube2t.S antibody, ube2t antibody
- 背景
-
Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway (PubMed:16916645, PubMed:17938197, PubMed:19111657, PubMed:19589784, PubMed:28437106). Also mediates monoubiquitination of FANCL and FANCI (PubMed:16916645, PubMed:17938197, PubMed:19111657, PubMed:19589784). May contribute to ubiquitination and degradation of BRCA1 (PubMed:19887602). In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination (PubMed:20061386).
Gene: UBE2T
- 分子量
- 22 kDa
- 基因ID
- 29089
- UniProt
- Q9NPD8
- 途径
- Chromatin Binding
-