EHMT1 抗体 (Internal Region)
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- 抗原 See all EHMT1 抗体
- EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EHMT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- EHMT1 Antibody detects endogenous levels of total EHMT1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human EHMT1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product EHMT1 Primary Antibody
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anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) (AA 1-100) antibody
EHMT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) antibodyEHMT1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) antibodyEHMT1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) antibodyEHMT1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1B7B4 unconjugated
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) (AA 1-100) antibodyEHMT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) (AA 1-260) antibodyEHMT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 有效期
- 12 months
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- 抗原
- EHMT1 (Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1))
- 别名
- EHMT1 (EHMT1 产品)
- 别名
- EUHMTASE1 antibody, Eu-HMTase1 antibody, FP13812 antibody, GLP antibody, GLP1 antibody, KMT1D antibody, bA188C12.1 antibody, EHMT1 antibody, G9a antibody, 9230102N17Rik antibody, D330003E03 antibody, mKIAA1876 antibody, bZ1O1.6 antibody, si:rp71-1o1.6 antibody, zgc:136244 antibody, euchromatic histone lysine methyltransferase 1 antibody, histone-lysine N-methyltransferase EHMT2 antibody, euchromatic histone-lysine N-methyltransferase 1 antibody, euchromatic histone methyltransferase 1 antibody, euchromatic histone-lysine N-methyltransferase 1a antibody, EHMT1 antibody, Ehmt1 antibody, LOC100121084 antibody, ehmt1 antibody, ehmt1a antibody
- 背景
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Description: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53.
Gene: EHMT1
- 分子量
- 170 kDa
- 基因ID
- 79813
- UniProt
- Q9H9B1
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