DDX20 抗体 (Internal Region)
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- 抗原 See all DDX20 抗体
- DDX20 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (DDX20))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DDX20 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- DDX20 Antibody detects endogenous levels of total DDX20.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human DDX20, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product DDX20 Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- DDX20 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (DDX20))
- 别名
- DDX20 (DDX20 产品)
- 别名
- DDX20 antibody, DP103 antibody, GEMIN3 antibody, dp103 antibody, Dp103 antibody, si:dkey-193l3.3 antibody, wu:fb16g08 antibody, wu:fb59a11 antibody, DEAD-box helicase 20 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 antibody, DDX20 antibody, ddx20 antibody, Ddx20 antibody
- 背景
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Description: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).
Gene: DDX20
- 分子量
- 92 kDa
- 基因ID
- 11218
- UniProt
- Q9UHI6
- 途径
- Ribonucleoprotein Complex Subunit Organization
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