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DDX20 抗体 (Internal Region)

This anti-DDX20 antibody is a 兔 多克隆 antibody detecting DDX20 in WB, ELISA, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6258109
发货至: 中国

Quick Overview for DDX20 抗体 (Internal Region) (ABIN6258109)

抗原

See all DDX20 抗体
DDX20 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (DDX20))

适用

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人, 小鼠

宿主

  • 35
  • 10

克隆类型

  • 36
  • 9
多克隆

标记

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This DDX20 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 7
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    • 1
    • 1
    • 1
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    Internal Region

    特异性

    DDX20 Antibody detects endogenous levels of total DDX20.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human DDX20, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    DDX20 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (DDX20))

    别名

    DDX20

    背景

    Description: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).

    Gene: DDX20

    分子量

    92 kDa

    基因ID

    11218

    UniProt

    Q9UHI6

    途径

    Ribonucleoprotein Complex Subunit Organization
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