-
- 抗原 See all CKLF 抗体
- CKLF (Chemokine-Like Factor (CKLF))
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CKLF antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CKLF6 Antibody detects endogenous levels of total CKLF6
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide
- 亚型
- IgG
- Top Product
- Discover our top product CKLF Primary Antibody
-
anti-Chemokine-Like Factor (CKLF) (AA 1-100) antibody
CKLF 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine-Like Factor (CKLF) (C-Term) antibodyCKLF 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine-Like Factor (CKLF) antibodyCKLF 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine-Like Factor (CKLF) (C-Term) antibodyCKLF 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine-Like Factor (CKLF) (AA 1-67) antibodyCKLF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine-Like Factor (CKLF) (N-Term) antibodyCKLF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
-
- 抗原
- CKLF (Chemokine-Like Factor (CKLF))
- 别名
- CKLF6 (CKLF 产品)
- 别名
- C32 antibody, CKLF1 antibody, CKLF2 antibody, CKLF3 antibody, CKLF4 antibody, UCK-1 antibody, 1700001C14Rik antibody, 1810018M11Rik antibody, CKLF5 antibody, Cklf2 antibody, Cklf6 antibody, HSPC224 antibody, Cklf1 antibody, chemokine like factor antibody, chemokine-like factor antibody, CKLF antibody, Cklf antibody, LOC100727126 antibody, LOC101103916 antibody
- 背景
-
Description: Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its STUB1-mediated ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.
Gene: CMTM6
- 分子量
- 25 kDa
- 基因ID
- 54918
- UniProt
- Q9NX76
-
You are here:
