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CDC42BPA 抗体 (Internal Region)

CDC42BPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258012
发货至: 中国
  • 抗原 See all CDC42BPA 抗体
    CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
    抗原表位
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Internal Region
    适用
    • 21
    • 11
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 17
    • 3
    • 1
    克隆类型
    • 18
    • 3
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDC42BPA antibody is un-conjugated
    应用范围
    • 9
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    CDC42BPA Antibody detects endogenous levels of total CDC42BPA.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CDC42BPA, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CDC42BPA Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CDC42BPA (CDC42 Binding Protein Kinase alpha (DMPK-Like) (CDC42BPA))
    别名
    CDC42BPA (CDC42BPA 产品)
    别名
    MRCK antibody, MRCKA antibody, PK428 antibody, Mrck antibody, Pk428 antibody, A930014J19Rik antibody, DMPK-like antibody, CDC42BPA antibody, CDC42 binding protein kinase alpha antibody, GDNF family receptor alpha 2 antibody, serine/threonine-protein kinase MRCK alpha antibody, CDC42 binding protein kinase alpha (DMPK-like) antibody, CDC42BPA antibody, Cdc42bpa antibody, GFRA2 antibody, LOC100182779 antibody, LOC100545977 antibody
    背景

    Description: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration (PubMed:15723050, PubMed:9418861, PubMed:9092543). Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates: PPP1R12A, LIMK1 and LIMK2 (PubMed:11340065, PubMed:11399775). May play a role in TFRC-mediated iron uptake (PubMed:20188707). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation (By similarity).

    Gene: CDC42BPA

    分子量
    97 kDa
    基因ID
    8476
    UniProt
    Q5VT25
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